January 22, 2019
Michael Notaras - "When does schizophrenia really begin?". Michael discussed cutting-edge research involving 3D stem cell bioengineering technology to design “mini-brains”, organoids that mimic the first trimester of brain development. Using this technology, he is able to study when mental disorders such as schizophrenia truly commence and the long term consequences for adult disease. Click here and here for video!
Reed Maxwell - "More than Ups and Downs: Everything You Didn't Know You Needed to Know about Borderline Personality Disorder". Reed discussed the ins and outs (and ups and downs) of Borderline Personality Disorder, including best treatments, how to recognize friends and loved ones who might have it, and how to help them out.
March 26, 2019
Brian Pickering - “The Epitranscriptome: small marks with big effects”. Genes give our cells the instructions necessary for life are expressed as RNA, which then makes proteins, which provide the structure and carry out most of the chemistry in our cells. With advances in technologies, we have discovered small chemical modifications that decorate our RNA, informing how much protein to make and how long to stick around before being degraded. Cancer cells hijack this process to proliferate indefinitely and resist treatment. Brian’s research investigates these processes with the goal of developing a new generation of therapeutics to fight cancer.
Fanny Vatter - "Exosomes: tiny messengers for big discoveries". Exosomes are vehicles released from cells, carrying molecules. The contents of an exosome can be used as a biomarker to determine the health or disease of a cell. Fannys research investigates the role of exosomes in breast cancer progression.
Wilhem Leconet - “Controlled delivery and targeting, future’s keywords in cancer therapy”. Wilhem's work focuses on a small therapeutic protein, named BiJ591, in prostate cancer. His research has provided new insights into the development of controlled delivery of small therapeutic proteins like BiJ591 in cancer, that once implemented, allow continued release of the therapeutic agent.
June 24, 2019
Melanie Balbach - “Survival of the fittest: A sperm's journey to fertilization”. The sperm overcomes a number of barriers on its way from ejaculation to an oocyte. Melanie will discuss how the physiology of the sperm adapts to overcome these barriers on it’s journey to fertilization, as well as how the uterus and the oocyte provide assistance to help the sperm reach its destination. Melanie's research investigating how the sperm fuels it’s engine to reach the oocyte can be used to develop male contraceptives and treat reproductive diseases.
Katherine Lopez - "Top Mouse: The Development of Social Dominance". Social dominance is an essential component of social behavior across a multitude of species, from insects to primates. The emergence of a dominant individual can be linked to genetics; however, this behavior develops even in genetically identical individuals in controlled laboratory settings. So, what makes an individual dominant? Is it nature (innate) or nurture (learnt)? Are all socially dominant individuals alike (e.g., are all dominant individuals aggressive/bullies?). These are a few of the questions that Katherine's research is currently exploring.
December 3, 2019
Get to know the real stars of the research show as four researchers from Weill Cornell Medicine will discuss the model organisms they use to conduct their cutting edge research. First, Spike Postnikoff will rise up to the task of discussing Yeast as a model organism. Swimming in next is Renuka Raman to represent the use of Zebrafish in research. Next up, you won’t need a microscope to see the impact that cells developed into Cerebral Organoids have on advancing research as we know it, presented by Mike Notaras. Finally, squeaking in to bring home the event, Divya Bhatia will talk about the versatility of transgenic mice. The event will conclude with a panel-style Q&A about the relevance of these models and how they are used in research.